Mycobacterium avium subspecies paratuberculosis as a cause of Crohn's disease
نویسندگان
چکیده
منابع مشابه
Does Mycobacterium avium subspecies paratuberculosis cause Crohn's disease?
Reassessing this persistent theory in light of advances in molecular microbial detection and genetic pathogenesis of disease.
متن کاملExploring the potential hazard of Mycobacterium avium subspecies paratuberculosis as a cause for Crohn’s disease
BACKGROUND Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne's disease (JD), or paratuberculosis in ruminants has been suspected to be implicated in the pathogenesis of Crohn's disease (CD) in humans with chronic inflammatory intestinal changes. As the hypothesis is now fast being recognized that MAP could possibly be the etiological agent of CD which is foun...
متن کاملThe Mycobacterium avium Subspecies Paratuberculosis Dilemma
The purpose of this paper is to present and update the longitudinal perspective of the Mycobacterium avium subspecies paratuberculosis dilemma as initially stated in Infectious Diseases Incorporated’s 2012 White Paper. In both wild and domestic herbivores, Mycobacterium avium subspecies paratuberculosis (MAP) produces chronic granulomatous enteritis (Johne’s disease) that, if unchecked, is usua...
متن کاملMycobacterium avium subspecies paratuberculosis and its relationship with Crohn's disease.
The hypothesis postulating that Mycobacterium avium paratuberculosis (MAP) is the cause of Crohn's disease (CD) has been circulating for many years. Advances in molecular techniques, such as polymerase chain reaction and culture methods, have enabled researchers to demonstrate that there is an association between MAP and CD. Recently, genome-wide association studies have identified novel suscep...
متن کاملMycobacterium avium subspecies paratuberculosis, Crohn's disease and the Doomsday scenario
Johne's disease is chronic inflammation of the intestine caused by Mycobacterium avium subspecies paratuberculosis. Infection and disease are mainly in domestic livestock but can affect many species including primates. Johne's is a new disease which emerged at the turn of the 19th and 20th centuries and principally involved Europe and North America. It has since spread to former low incidence r...
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ژورنال
عنوان ژورنال: Gut
سال: 2003
ISSN: 0017-5749
DOI: 10.1136/gut.52.1.155